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MicroProtein Technologies

The First Company to Produce Recombinant Biologics on an Industrial Scale Without Using the Conventional Fermentation Process.

MicroProtein Technologies Inc., was founded by Vinod Pandiripally Ph.D. with the purpose of commercializing novel and cutting-edge methods for the culture of E. coli to produce recombinant biologics (proteins and plasmid DNA)

About Us

A Pioneer In The Field Of BioTechnology

After years of proprietary research and development, MPT has developed a robust solid media-based E. coli manufacturing platform, MPTxpress, which far surpasses conventional fermentation as a reliable and inexpensive way to produce recombinant proteins.

MPTxpress has advantages including higher yields with incredible simplicity and related cost savings, including no need for bioreactors, mixers, etc.; is fully singleuse; minimizes up-stream and down-stream processing; and eliminates the need for expensive fixed stainless steel equipment. E. coli is cultured on top of a membrane laid on top of 12-inch square agar plates, with harvesting involving scraping concentrated protein paste off the membrane. Each plate produces >1 gram of protein after incubation overnight at room temperature in a standard lab. incubator. MPTxpress is scalable to commercial manufacture, e.g., ≥1 kg/day – simply use more trays (mini bioreactors in parallel)

Who We Are

We Provide CDMO, CMO, CRO services Commercializing recombinant biologics & recombinant proteins

MicroProtein Technologies Inc. (MPT) is a pioneer in the field of biotechnology, offering CDMO, CMO, CRO services using MPTxpress, a unique solid-state/liquids- and stress-free E. coli. manufacturing platform; and commercializing other antibody affinity proteins and resins with greatly improved pH tolerance and than competing resins. Using our patented MPTxpress technology, we aim to lead the industry in the production of microbially-expressed recombinant proteins, enzymes and plasmid DNA for use in biopharmaceuticals, diagnostics, reagents, veterinary medicine, non-clinical academic and industrial applications. Read more …..

50mg Package

Recombinant Streptavidin

Formulation: Lyophilized Salt-free powder
Product#: MPT-SA-100

$270.00 USD each

0.5mg Package

Recombinant human IL-2

Formulation: Lyophilized Salt-free powder
Product#: hIL-2L0.5mg

$423.00 USD each

20mg Package

Recombinant Protein A

Formulation: Lyophilized Salt-free powder
Product#: A100L20

$53.00 USD each

25mg Package

Recombinant Protein G

Formulation: Lyophilized Salt-free powder
Product#: G100L20

$99.00 USD each

10mg Package

Recombinant Protein AG

Formulation: Lyophilized Salt-free powder
Product#: AG100L10

$75.00 USD each

10mg Package

Recombinant Protein L

Formulation: Lyophilized Salt-free powder
Product#: L100L10

$159.00 USD each

Our Services

What Service We Offer

Contract Research Organization (CRO)

During the research and development of protein-based therapeutics, finding the optimal conditions for protein production is often a time-consuming and laborintensive process.

Contract Manufacturing Organization (CMO)

The R&D pipeline for new drugs has changed considerably over the past decade. Once dominated by big pharma and small molecules, today’s pipeline is increasingly populated with small and emerging biotech companies developing large molecules, or biologics, which now make up nearly 40% of the active R&D pipeline globally.

Our Products

What Products We Offer

Streptavidin

Streptavidin is a biotin-binding protein found in culture broth of the bacterium Streptomyces avidin. Streptavidin binds 4 moles of biotin per mole of protein
with a remarkably high affinity.

Carrier-Free Human Interleukin-2

Interleukin-2 (IL-2) is one of a family of polypeptides that mediate interactions between leukocytes. It is a T-cell growth factor.

Recombinant Protein A

Proprietary recombinant Protein A
is produced using our proprietary
MPTxpress solid-state E. coli expression system.
This Protein A functions essentially the same as native Protein A.

Recombinant Protein G

The gene we selected to use for the production of Protein G originated from Streptococcus Strain G148, and was cloned and expressed in our proprietary strain of Escherichia coli.


Recombinant Protein AG

Our recombinant Protein A/G is a fusion protein that comprises of a total of 7 IgG-binding domains EDABC-C2C3. This fusion protein combines the active Fc-binding domains of Protein A and Protein G that are contained in the recombinant sequence.

Recombinant Protein L

Recombinant Protein L is expressed by MicroProtein Technologies in E.coli using its MPTxpress upstream platform with innovative purification methods.